Article
T‐box transcription factor Tbx2 represses differentiation and formation of the cardiac chambers
25 Feb 2004
Abstract excerpt
Specific regions of the embryonic heart tube differentiate into atrial and ventricular chamber myocardium, whereas the inflow tract, atrioventricular canal, inner curvatures, and outflow tract do not. These regions express Tbx2, a transcriptional repressor. Here, we tested its role in chamber formation. The temporal and spatial pattern of Tbx2 mRNA and protein expression in mouse hearts was found to be...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
