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Article

Tbx1 is a negative modulator of Mef2c.

Human molecular genetics - 1 Jun 2012

Pane Luna Simona, Zhang Zhen, Ferrentino Rosa, Huynh Tuong, Cutillo Luisa, Baldini Antonio

Abstract excerpt

The developmental role of the T-box transcription factor Tbx1 is exquisitely dosage-sensitive. In this study, we performed a microarray-based transcriptome analysis of E9.5 embryo tissues across a previously generated Tbx1 mouse allelic series. This analysis identified several genes whose express...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22367967
DOI: 10.1093/hmg/dds063
PMCID: PMC3349424

Genes

SHF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22367967-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Tbx1 is a negative modulator of Mef2c.PMID 22367967Read ↗

Tbx1: Transcriptional and Developmental Functions.Semantic proximity Read ↗

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Tbxl represses <i>Mef2c</i> gene expression by inducing histone 3 deacetylation of the anterior heart field enhancerSemantic proximity Read ↗

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Regulatory mutants of the <i>Tbx1</i> gene alter transcription programs of lineage determination and patterning in early mesodermSemantic proximity Read ↗

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