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Article

Tbx1 is a negative modulator of Mef2c.

Human molecular genetics - 1 Jun 2012

Pane Luna Simona, Zhang Zhen, Ferrentino Rosa, Huynh Tuong, Cutillo Luisa, Baldini Antonio

Abstract excerpt

The developmental role of the T-box transcription factor Tbx1 is exquisitely dosage-sensitive. In this study, we performed a microarray-based transcriptome analysis of E9.5 embryo tissues across a previously generated Tbx1 mouse allelic series. This analysis identified several genes whose expression was affected by Tbx1 dosage. Interestingly, we found that the expression of the gene encoding the cardiogenic...

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Identifiers

PMID: 22367967
DOI: 10.1093/hmg/dds063
PMCID: PMC3349424

Genes

SHF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Tbx1 is a negative modulator of Mef2c.PMID 22367967Read ↗

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