Article
Headless flies produced by mutations in the paralogous Pax6 genes eyeless and twin of eyeless.
Development (Cambridge, England) - 1 Feb 2002
Kronhamn Jesper, Frei Erich, Daube Michael, Jiao Renjie, Shi Yandong, Noll Markus, Rasmuson-Lestander Asa
Abstract excerpt
The two Pax6 gene homologs eyeless and twin of eyeless play decisive early roles in Drosophila eye development. Strong mutants of twin of eyeless or of eyeless are headless, which suggests that they are required for the development of all structures derived from eye-antennal discs. The activity of these genes is crucial at the very beginning of eye-antennal development in the primordia of eye-antennal discs when...
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