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Article

The Drosophila Pax6 paralogs have different functions in head development but can partially substitute for each other.

Molecular genetics and genomics : MGG - 1 Sept 2009

Jacobsson Linn, Kronhamn Jesper, Rasmuson-Lestander Asa

Abstract excerpt

There are two Pax6 genes in Drosophila melanogaster; eyeless (ey) and twin-of-eyeless (toy), due to a duplication, which most likely occurred in the insect lineage. They encode transcription factors important for head development. Misexpression of either toy or ey can induce formation of ectopic compound eyes. Toy regulates the ey gene by binding to an eye-specific enhancer in its second intron. However, Toy can...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19484263
DOI: 10.1007/s00438-009-0458-2
PMCID: PMC2729988

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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