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Article

Functional analysis of an eye specific enhancer of the eyeless gene in Drosophila.

Proceedings of the National Academy of Sciences of the United States of America - 19 Jan 1999

Hauck B, Gehring W J, Walldorf U

Abstract excerpt

The development of the Drosophila compound eye requires the function of a set of evolutionarily conserved genes. Among these, the Drosophila Pax-6 gene eyeless (ey) plays a major role. ey has been considered a master control gene of eye development in the animal kingdom because targeted expression of ey and vertebrate as well as invertebrate homologs lead to the formation of ectopic eyes in Drosophila. We...

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Identifiers

PMID: 9892673
DOI: 10.1073/pnas.96.2.564
PMCID: PMC15176

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Functional analysis of an eye specific enhancer of the eyeless gene in Drosophila.PMID 9892673Read ↗

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The Drosophila Pax6 paralogs have different functions in head development but can partially substitute for each other.Semantic proximity Read ↗

Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila.Semantic proximity Read ↗

Regulation of twin of eyeless during Drosophila development.Semantic proximity Read ↗

The Drosophila eyes absent gene directs ectopic eye formation in a pathway conserved between flies and vertebrates.Semantic proximity Read ↗

Eye specification in Drosophila: perspectives and implications.Semantic proximity Read ↗

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Two Pax genes, eye gone and eyeless, act cooperatively in promoting Drosophila eye development.Semantic proximity Read ↗

Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development.Semantic proximity Read ↗

The master control gene for morphogenesis and evolution of the eye.Semantic proximity Read ↗

Mutational analysis of the eyeless gene and phenotypic rescue reveal that an intact Eyeless protein is necessary for normal eye and brain development in Drosophila.Semantic proximity Read ↗

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