Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development.

doi:10.1242/dev.125.12.2181

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Article

Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development.

Development (Cambridge, England) - 1 Jun 1998

Halder G, Callaerts P, Flister S, Walldorf U, Kloter U, Gehring W J

Abstract excerpt

The Drosophila Pax-6 gene eyeless acts high up in the genetic hierarchy involved in compound eye development and can direct the formation of extra eyes in ectopic locations. Here we identify sine oculis and eyes absent as two mediators of the eye-inducing activity of eyeless. We show that eyeless...

Topics

Animals
Cell Death
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Eye
Eye Proteins
Gene Expression Regulation, Developmental
Genes, Insect
Homeodomain Proteins
Morphogenesis
Mutation
Phenotype

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