Article
Pax proteins and eye development.
Current opinion in neurobiology - 1 Feb 1996
Macdonald R, Wilson S W
Abstract excerpt
Homologous members of the Pax gene family are required for eye development in Drosophila and vertebrates. Despite superficial similarities in the phenotypes of vertebrates with mutations in pax-6 and Drosophila eyeless mutants, it remains uncertain whether the two proteins encoded by these genes have comparable functions. The genetic cascade triggered by eyeless leads to eye formation, whereas pax-6 is not...
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