Article
Eye specification in Drosophila: perspectives and implications.
Seminars in cell & developmental biology - 1 Dec 2001
Kumar J P, Moses K
Abstract excerpt
The discovery that Drosophila eyeless is homologous to vertebrate Pax6 produced enormous interest in eye specification and a reappraisal of eye evolution. While the transcription factor Eyeless/Pax6 is necessary and in some circumstances sufficient to induce eye development the simple story of eye specification has become more epic than haiku. At least seven other nuclear proteins act with Eyeless/Pax6 to induce...
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