Article
Evidence for the murine IgH mu locus acting as a hot spot for intrachromosomal homologous recombination.
Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2002
Raynard Steven J, Read Leah R, Baker Mark D
Abstract excerpt
Homologous recombination accomplishes the exchange of genetic information between two similar or identical DNA duplexes. It can occur either by gene conversion, a process of unidirectional genetic exchange, or by reciprocal crossing over. Homologous recombination is well known for its role in generating genetic diversity in meiosis and, in mitosis, as a DNA repair mechanism. In the immune system, the evidence...
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