Article
A non-hypervariable human minisatellite strongly stimulates in vitro intramolecular homologous recombination.
Journal of molecular biology - 8 May 1998
Boán F, Rodríguez J M, Gómez-Márquez J
Abstract excerpt
Several features indicate that the low polymorphic human minisatellite MsH42 region could be involved in recombination. It contains different well-known recombination motifs, is able to generate single-stranded loops and is specifically recognized by nuclear proteins. These characteristics led us...
Topics
- Animals
- Base Sequence
- Cell Line
- Crossing Over, Genetic
- Genetic Variation
- Humans
- Liver
- Male
- Mice
- Minisatellite Repeats
- Models, Genetic
- Plasmids
- Polymorphism, Genetic
- Recombinant Proteins
- Recombination, Genetic
- Testis
- beta-Galactosidase