Article
Ea recombinational hot spot in the mouse major histocompatibility complex maps to the fourth intron of the Ea gene.
Genome research - 1 Mar 1996
Khambata S, Mody J, Modzelewski A, Heine D, Passmore H C
Abstract excerpt
The majority of recombination events detected within the mouse major histocompatibility complex (MHC) fall into regions of limited physical distance known as hot spots of meiotic recombination. The hot spot associated with the Ea gene appears to be active only in the presence of the p allele carr...
Topics
- Alleles
- Animals
- Base Sequence
- Chromosome Mapping
- Exons
- Genes, MHC Class I
- Genetic Markers
- Introns
- Mice
- Mice, Inbred C57BL
- Microsatellite Repeats
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Recombination, Genetic