Article
Functional analysis and case-control study of -160C/A polymorphism in the E-cadherin gene promoter: association with cancer risk.
Anticancer research - 1 Jan 2000
Cattaneo Francesca, Venesio Tiziana, Molatore Sara, Russo Antonio, Fiocca Roberto, Frattini Milo, Scovassi A Ivana, Ottini Laura, Bertario Lucio, Ranzani Guglielmina Nadia
Abstract excerpt
BACKGROUND: A C-->A polymorphism within the CDH1 (E-cadherin) promoter seems to be associated with a reduced efficiency of gene transcription in vitro. Due to the crucial role of E-cadherin in epithelia, tissue-specific effect of C-->A change on CDH1 transcription was tested and a case-control st...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
