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Article

E-cadherin polymorphisms and haplotypes influence risk for prostate cancer.

The Prostate - 1 Apr 2006

Bonilla Carolina, Mason Tshela, Long Layron, Ahaghotu Chiledum, Chen Weidong, Zhao Aiqiu, Coulibaly Aoua, Bennett Frankly, Aiken William, Tullock Trevor, Coard Kathleen, Freeman Vincent, Kittles Rick A

Abstract excerpt

BACKGROUND: The E-cadherin (CDH1) gene has been implicated in prostate cancer (PCA) risk, however, the exact mechanism is unknown. Several polymorphisms, such as the C/A variant -160 base pairs from the transcription start site, in the CDH1 gene promoter region have been associated with cancer risk, mainly in European descent populations. METHODS: We screened the entire coding region and 3.0 kilobases of the CDH1...

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Identifiers

PMID: 16372334
DOI: 10.1002/pros.20374

Genes

CDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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