Article
Quinones in long-lived clk-1 mutants of Caenorhabditis elegans.
FEBS letters - 13 Feb 2002
Miyadera Hiroko, Kano Kenji, Miyoshi Hideto, Ishii Naoaki, Hekimi Siegfried, Kita Kiyoshi
Abstract excerpt
Ubiquinone (UQ) (coenzyme Q) is a lipophilic redox-active molecule that functions as an electron carrier in the mitochondrial electron transport chain. Electron transfer via UQ involves the formation of semiubiquinone radicals, which causes the generation of superoxide radicals upon reaction with oxygen. In the reduced form, UQ functions as a lipid-soluble antioxidant, and protects cells from lipid peroxidation....
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