Molecular genetics of ubiquinone biosynthesis in animals.

doi:10.3109/10409238.2012.741564

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Article

Molecular genetics of ubiquinone biosynthesis in animals.

Critical reviews in biochemistry and molecular biology - 1 Jan 2000

Wang Ying, Hekimi Siegfried

Abstract excerpt

Ubiquinone (UQ), also known as coenzyme Q (CoQ), is a redox-active lipid present in all cellular membranes where it functions in a variety of cellular processes. The best known functions of UQ are to act as a mobile electron carrier in the mitochondrial respiratory chain and to serve as a lipid soluble antioxidant in cellular membranes. All eukaryotic cells synthesize their own UQ. Most of the current knowledge...

Topics

Animals
Ataxia
Humans
Mitochondrial Diseases
Muscle Weakness
Mutation
Phenotype
Ubiquinone

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Identifiers

PMID: 23190198
DOI: 10.3109/10409238.2012.741564
PMCID: PMC4053409

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