Article
Complementation of Escherichia coli ubiF mutation by Caenorhabditis elegans CLK-1, a product of the longevity gene of the nematode worm.
FEBS letters - 22 May 2003
Adachi Akihiko, Shinjyo Noriko, Fujita Daisuke, Miyoshi Hideto, Amino Hisako, Watanabe Yoh ichi, Kita Kiyoshi
Abstract excerpt
Caenorhabditis elegans CLK-1 was identified from long-lived mutant worms, and is believed to be involved in ubiquinone biosynthesis. The protein belongs to the eukaryotic CLK-1/Coq7p family, which is also similar to the bacterial Coq7 family, that hydroxylates demethoxyubiquinone, resulting in the formation of hydroxyubiquinone, a precursor of ubiquinone. In Escherichia coli, the corresponding reaction is...
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