Article
Elevated plasma activator inhibitor 1 is not related to insulin resistance and to gene polymorphism in healthy centenarians.
Atherosclerosis - 1 Feb 2002
Rizzo Maria Rosaria, Ragno Emilia, Barbieri Michelangela, De Lucia Domenico, Manzella Daniela, Tagliamonte Maria Rosaria, Colaizzo Donatella, Margaglione Maurizio, Paolisso Giuseppe
Abstract excerpt
Previous studies demonstrated a relationship between the degree of insulin resistance and plasma plasminogen activator inhibitor type-1 (PAI-1) levels. We aim at investigating the relationship between the degree of insulin resistance and plasma PAI-1 levels in aged subjects (n=83) and in healthy centenarians (n=42). In all subjects the degree of insulin resistance was assessed by HOMA method. Our data...
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