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Article

PAI-1, obesity, insulin resistance and risk of cardiovascular events.

Thrombosis and haemostasis - 1 Jul 1997

Juhan-Vague I, Alessi M C

Abstract excerpt

Circulating (PAI-1) levels are elevated in patients with coronary heart disease and may play an important role in the development of atherothrombosis. Many clinical studies have indicated that the insulin resistance syndrome, which is a situation predisposing to diabetes and ischemic heart disease, may be a major regulator of PAI-1 expression, especially in determining plasma PAI-1 levels. Central obesity is a...

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Source

Identifiers

PMID: 9198234

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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