PAI-1 concentrations in first-degree relatives of patients with non-insulin-dependent diabetes: metabolic and genetic associations.

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Article

PAI-1 concentrations in first-degree relatives of patients with non-insulin-dependent diabetes: metabolic and genetic associations.

Thrombosis and haemostasis - 1 Feb 1997

Mansfield M W, Stickland M H, Grant P J

Abstract excerpt

AIM: To identify whether levels of PAI-1 are elevated in relatives of NIDDM patients and the extent to which they relate to features of insulin resistance and to genotype at a common PAI-1 promoter polymorphism. RESULTS: In 132 first-degree relatives of NIDDM patients and 151 controls PAI-1 activ...

Topics

Adult
Arteriosclerosis
Blood Glucose
Blood Pressure
Body Mass Index
Diabetes Mellitus, Type 2
England
Family
Female
Genotype
Glycated Hemoglobin
Humans
Insulin Resistance
Lipids
Male
Middle Aged
Plasminogen Activator Inhibitor 1
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 9157596

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9157596-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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