Article
PAI-1 concentrations in first-degree relatives of patients with non-insulin-dependent diabetes: metabolic and genetic associations.
Thrombosis and haemostasis - 1 Feb 1997
Mansfield M W, Stickland M H, Grant P J
Abstract excerpt
AIM: To identify whether levels of PAI-1 are elevated in relatives of NIDDM patients and the extent to which they relate to features of insulin resistance and to genotype at a common PAI-1 promoter polymorphism. RESULTS: In 132 first-degree relatives of NIDDM patients and 151 controls PAI-1 activity was higher in relatives 14.4 U/ml than controls 9.3 U/ml (p < 0.0005) with higher body mass index 27.3 v. 24.7...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.