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Article

Low circulating IGF-I bioactivity is associated with human longevity: Findings in centenarians’ offspring

9 Sept 2012

Abstract excerpt

UNLABELLED: Centenarians' offspring represent a suitable model to study age-dependent variables (e.g. IGF-I) potentially involved in the modulation of the lifespan. The aim of the present study was to investigate the role of the IGF-I in human longevity. We evaluated circulating IGF-I bioactivity measured by an innovative IGF-I Kinase Receptor Activation (KIRA) Assay, total IGF-I, IGFBP-3, total IGF-II, insulin,...

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Share to Birth, Development, and Health
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PMID: 22983440
DOI: 10.18632/aging.100484

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