Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasma plasminogen activator inhibitor 1, insulin resistance and android obesity.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Dec 1999

Bastard J P, Piéroni L

Abstract excerpt

Plasma plasminogen activator inhibitor 1 (PAI-1) levels are elevated in insulin-resistant subjects and are associated with increased cardiovascular risk of atherothrombosis. Strong association between PAI-1 and the metabolic components of the insulin resistance syndrome is found in clinical studies, suggesting that insulin resistance may regulate circulating PAI-1. However, the mechanisms underlying increased...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue
Share to Arteriosclerosis
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperinsulinism

Share to Insulin Resistance

Share to Obesity

Share to Plasminogen Activator Inhibitor 1

Source

Identifiers

PMID: 10665338
DOI: 10.1016/s0753-3322(00)88103-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasma plasminogen activator inhibitor 1, insulin resistance and android obesity.PMID 10665338Read ↗

PAI-1, obesity, insulin resistance and risk of cardiovascular events.Semantic proximity Read ↗

Relationship between plasma plasminogen activator inhibitor 1 and insulin resistance.Semantic proximity Read ↗

Insulin resistance, plasma PAI-1 levels and PAI-1 gene polymorphism in healthy centenarians.Semantic proximity Read ↗

Insulin resistance: an atherothrombotic syndrome. The Leeds family study.Semantic proximity Read ↗

Elevated plasma activator inhibitor 1 is not related to insulin resistance and to gene polymorphism in healthy centenarians.Semantic proximity Read ↗

Targeted expression of plasminogen activator inhibitor(PAI)-1 to the stomach inhibits gut-brain signalling by the satiety hormone cholecystokinin (CCK)Semantic proximity Read ↗

Body adiposity but not insulin resistance is associated with -675 4G/5G polymorphism in the PAI-1 gene in a sample of Mexican children.Semantic proximity Read ↗

[Android-type obesity and gynecoid-type obesity].Semantic proximity Read ↗

PAI-1 concentrations in first-degree relatives of patients with non-insulin-dependent diabetes: metabolic and genetic associations.Semantic proximity Read ↗

Role of the 4G/5G polymorphism of PaI-1 gene promoter on PaI-1 levels in obese patients: influence of fat distribution and insulin-resistance.Semantic proximity Read ↗

Effect of plasminogen activator inhibitor-1 deficiency on nutritionally-induced obesity in mice.Semantic proximity Read ↗

A promoter genotype and oxidative stress potentially link resistin to human insulin resistance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.