Article
Relationship between plasma plasminogen activator inhibitor 1 and insulin resistance.
Diabetes/metabolism research and reviews - 1 Jan 2000
Bastard J P, Piéroni L, Hainque B
Abstract excerpt
High plasminogen activator inhibitor 1 (PAI-1) levels are associated with an increased cardiovascular risk of atherothrombosis. Furthermore, increased plasma PAI-1 levels are associated with dyslipidemia, hyperinsulinemia and hypertension. This association between PAI-1 and metabolic components of the Metabolic Syndrome could explain the predisposition of insulin resistant patients to atherothrombosis. Recent...
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