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Glucose regulation and oxidative stress in healthy centenarians.

Experimental gerontology - 1 Jan 2000

Barbieri Michelangela, Rizzo Maria Rosaria, Manzella Daniela, Grella Rodolfo, Ragno Emilia, Carbonella Marco, Abbatecola Angela Marie, Paolisso Giuseppe

Abstract excerpt

Aging, oxidative stress and insulin resistance are strongly correlated. There is a growing body of evidence showing that aging is associated with a significant rise in oxidative stress mainly due to a decline in anti-oxidant activity and a rise in pro-oxidant factors such as glucose and insulin concentrations. Furthermore, aging is also associated with a progressive rise in insulin resistance which is due to a...

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PMID: 12543271
DOI: 10.1016/s0531-5565(02)00153-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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