Article
Motheaten, an immunodeficient mutant of the mouse. I. Genetics and pathology.
The Journal of heredity - 1 Jan 2000
Green M C, Shultz L D
Abstract excerpt
A new recessive mutation, motheaten (me), is on chromosome 6, 21.9 +/- 4.3 recombination units distal to white (Miwh). Mice homozygous for the new mutation have neutrophilic lesions of the skin beginning as early as day 1, and pneumonitis with many macrophages in the alveoli as early as day 3. They suffer high mortality from birth onward and none has survived longer than 8 weeks. The lymph nodes may be enlarged,...
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