Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A differential gene expression study: Ptpn6 (SHP-1)-insufficiency leads to neutrophilic dermatosis-like disease (NDLD) in mice.

Journal of dermatological science - 1 Jul 2016

Nesterovitch Andrew B, Arbieva Zarema, Toth Daniel M, Tharp Michael D, Glant Tibor T

Abstract excerpt

BACKGROUND: Irradiated syngeneic wild-type mice developed the same neutrophilic dermatosis-like disease (NDLD) after adoptive transfer of bone marrow cells from Ptpn6(meb2/meb2) mutant mice. OBJECTIVE: To analyze differentially expressed genes in the bone marrow of mice with NDLD to gain insight into the role of Ptpn6 in myelopoietic bone marrow pathology, and the mechanisms by which Ptpn6 insufficiency in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow Cells
Share to Immunity, Innate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-1beta

Share to Lectins, C-Type

Share to Neutrophils

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 6

Share to Toll-Like Receptors

Source

Identifiers

PMID: 27020408
DOI: 10.1016/j.jdermsci.2016.03.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A differential gene expression study: Ptpn6 (SHP-1)-insufficiency leads to neutrophilic dermatosis-like disease (NDLD) in mice.PMID 27020408Read ↗

Spontaneous insertion of a b2 element in the ptpn6 gene drives a systemic autoinflammatory disease in mice resembling neutrophilic dermatosis in humans.Semantic proximity Read ↗

Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice.Semantic proximity Read ↗

Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease.Semantic proximity Read ↗

Alteration in the gene encoding protein tyrosine phosphatase nonreceptor type 6 (PTPN6/SHP1) may contribute to neutrophilic dermatoses.Semantic proximity Read ↗

Immune-Related Genes Associated with Interstitial Lung Disease in DermatomyositisSemantic proximity Read ↗

Dynamic pathological analysis reveals a protective role against skin fibrosis for TREM2-dependent macrophagesSemantic proximity Read ↗

Immune-related genes probably increase the occurrence of Interstitial Lung Disease in DermatomyositisSemantic proximity Read ↗

Microarray Gene Expression Analysis of Lesional Skin in Canine Pemphigus FoliaceusSemantic proximity Read ↗

High resolution profile of body wide pathological changes induced by abnormal elastin metabolism in Loxl1 knockout miceSemantic proximity Read ↗

Sex-dimorphic expression of extracellular matrix genes in mouse bone marrow neutrophilsSemantic proximity Read ↗

Loss of Shp1 impairs myeloid cell function and causes lethal inflammation in zebrafish larvaeSemantic proximity Read ↗

Wiskott–Aldrich Syndrome Protein Deficiency in Innate Immune Cells Leads to Mucosal Immune Dysregulation and Colitis in MiceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.