Article
Forward genetic dissection of innate response to infection in inbred mouse strains: selected success stories.
Clinical and experimental immunology - 1 Dec 2010
Gruenheid S, Gros P
Abstract excerpt
Mouse genetics is a powerful tool for the dissection of genes, proteins, and pathways important in biological processes. Application of this approach to study the host response to infection has been a rich source of discoveries that have increased our understanding of the early innate pathways involved in responding to microbial infections. Here we review some of the key discoveries that have arisen from...
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