Article
Genetic polymorphisms in microsomal epoxide hydrolase and susceptibility to adult acute myeloid leukaemia with defined cytogenetic abnormalities.
British journal of haematology - 1 Mar 2002
Lebailly Pierre, Willett Eleanor V, Moorman Anthony V, Roman Eve, Cartwright Ray, Morgan Gareth J, Wild Christopher P
Abstract excerpt
Acute myeloid leukaemia (AML) cases with different chromosomal abnormalities may reflect different aetiologies. Benzene exposure, from a number of sources including smoking, is one risk factor for AML. Individual susceptibility to benzene may depend on differences in expression of metabolizing enzymes. We tested the hypothesis that smoking as well as genetic polymorphisms in the microsomal epoxide hydrolase gene...
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