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Article

Variation in genes relevant to aromatic hydrocarbon metabolism and the risk of adult brain tumors.

Neuro-oncology - 1 Apr 2006

De Roos Anneclaire J, Rothman Nathaniel, Brown Merideth, Bell Douglas A, Pittman Gary S, Shapiro William R, Selker Robert G, Fine Howard A, Black Peter M, Inskip Peter D

Abstract excerpt

Genes involved in phase I and phase II regulation of aromatic hydrocarbon-induced effects exhibit sequence variability that may mediate the risk of adult brain tumors. We evaluated associations between gene variants in CYP1A1, CYP1B1, GSTM3, EPHX1, and NQO1 and adult brain tumor incidence. Cases were patients with glioma (n = 489), meningioma (n = 197), or acoustic neuroma (n = 96) diagnosed from 1994 to 1998 at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16598069
DOI: 10.1215/15228517-2005-003
PMCID: PMC1871937

Genes

GSTM3
EPHX1
NQO1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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