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Article

Microsomal epoxide hydrolase (EPHX1) polymorphisms are associated with aberrant promoter methylation of ERCC3 and hematotoxicity in benzene-exposed workers.

Environmental and molecular mutagenesis - 1 Jul 2013

Xing Caihong, Chen Qi, Li Guilan, Zhang Linyuan, Zheng Min, Zou Zhengyong, Hou Lifang, Wang Qian-Fei, Liu Xin, Guo Xinbiao

Abstract excerpt

Benzene is an important industrial chemical and widespread environmental pollutant known to induce leukemia and other blood disorders. To be carcinogenic, benzene must be metabolized to produce toxic metabolites. To investigate whether single nucleotide polymorphisms (SNPs) in the metabolic enzym...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23797950
DOI: 10.1002/em.21786

Genes

EPHX1
ERCC3
NQO1
BLM
NUDT1
RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23797950-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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