Presence of p53 mutation in human cervical carcinomas associated with HPV-33 infection.

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Article

Presence of p53 mutation in human cervical carcinomas associated with HPV-33 infection.

Anticancer research - 1 Jan 2000

Lo K W, Mok C H, Chung G, Huang D P, Wong F, Chan M, Lee J C, Tsao S W

Abstract excerpt

In this present study, we report the mutation of the p53 gene in vivo in human primary carcinomas of cervix and cervical intraepithelial neoplasia (CIN). The association of the HPV subtypes with the tumors was determined by multiplex primer polymerase chain reaction (PCR) amplification. The mutation of the p53 gene was detected using PCR amplification of the p53 exons followed by SSCP (single strand conformation...

Topics

Amino Acid Sequence
Base Sequence
Chromosomes, Human, Pair 17
Codon
DNA Probes
DNA, Neoplasm
Female
Genes, p53
Heterozygote
Humans
Introns
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Neoplasm Staging

Papillomaviridae

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Tumor Virus Infections

Source

Open in PubMed

Identifiers

PMID: 1363512

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1363512-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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