Article
Bracken fern-induced malignant tumors in rats: absence of mutations in p53, H-ras and K-ras and no microsatellite instability.
Mutation research - 20 Feb 2002
Freitas Renata N, Brasileiro-Filho Geraldo, Silva Marcelo E, Pena Sérgio D J
Abstract excerpt
Bracken fern (genus Pteridium) has been shown to induce tumors in domestic and experimental animals. Epidemiological studies have also shown an association between human exposure to bracken toxins and increased risk for the development of upper gastrointestinal tract tumors. Our aim in this study was to investigate possible genomic alterations in bracken fern-induced tumors of experimental animals searching for...
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