Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The potential use of mutation spectra in cancer related genes in genetic toxicology: a statement of a GUM working group.

Mutation research - 20 Feb 2001

Hartwig A, Kasper P, Madle S, Speit G, Staedtler F, Sengstag C

Abstract excerpt

In recent years, there has been widespread interest in the relationship between carcinogenic exposure and mutation spectra in cancer-related genes. To evaluate potential benefits and/or limitations in the use of mutation spectra in genetic toxicology, a GUM working group has been established to discuss this subject. Based on methodological possibilities and limitations, the impact of mutation spectra in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinogenicity Tests
Share to Carcinogens
Share to Genes, p53

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, ras

Share to Mutagenicity Tests

Share to Mutation

Share to Neoplasms

Source

Identifiers

PMID: 11166044
DOI: 10.1016/s0027-5107(00)00139-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The potential use of mutation spectra in cancer related genes in genetic toxicology: a statement of a GUM working group.PMID 11166044Read ↗

Mutation spectra resulting from carcinogenic exposure: from model systems to cancer-related genes.Semantic proximity Read ↗

Human cancer, carcinogenic exposures and mutation spectra.Semantic proximity Read ↗

Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part IV:Recommendation of a Working Group of the Gesellschaft fuer Umwelt-Mutationsforschung (GUM) for a Simple and Straightforward Approach to Genotoxicity TestingSemantic proximity Read ↗

Mutational spectrometry in animal toxicity testing.Semantic proximity Read ↗

p53 mutation spectrum and load: the generation of hypotheses linking the exposure of endogenous or exogenous carcinogens to human cancer.Semantic proximity Read ↗

Modelling Mutation Spectra of Human Carcinogens Using Experimental Systems.Semantic proximity Read ↗

Mechanistic insights from biomarker studies: somatic mutations and rodent/human comparisons following exposure to a potential carcinogen.Semantic proximity Read ↗

New approaches to understanding p53 gene tumor mutation spectra.Semantic proximity Read ↗

Experimental investigations of carcinogen-induced mutation spectra: Innovation, challenges and future directions.Semantic proximity Read ↗

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT).Semantic proximity Read ↗

The mammalian gene mutation database.Semantic proximity Read ↗

Molecular epidemiology of human cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.