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Article

Alterations in the K-ras and p53 genes in rat lung tumors.

Environmental health perspectives - 1 Jun 1997

Belinsky S A, Swafford D S, Finch G L, Mitchell C E, Kelly G, Hahn F F, Anderson M W, Nikula K J

Abstract excerpt

Activation of the K-ras protooncogene and inactivation of the p53 tumor suppressor gene are events common to many types of human cancers. Molecular epidemiology studies have associated mutational profiles in these genes with specific exposures. The purpose of this paper is to review investigation...

Topics

Animals
DNA Damage
Genes, p53
Genes, ras
Lung Neoplasms
Mutation
Nuclear Proteins
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-mdm2
Rats

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9255578
DOI: 10.1289/ehp.97105s4901
PMCID: PMC1470039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9255578-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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