Article
[Profile of p53 mutations and abnormal expression of P53 protein in 2 forms of esophageal cancer].
Gastroenterologie clinique et biologique - 1 Jan 1996
Muzeau F, Fléjou J F, Potet F, Belghiti J, Thomas G, Hamelin R
Abstract excerpt
AIMS AND METHODS: p53 tumor suppressor gene is involved in the development of esophageal cancer. However, its role is not precisely defined in the two types of cancer, squamous cell carcinoma and adenocarcinoma developed in Barrett's esophagus. The aim of this work was to compare the frequency and type of mutation of the p53 gene and the expression of the p53 protein in a series of 21 squamous cell carcinomas and...
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