Article
Frequent loss of heterozygosity in chromosomal region 9pter-p13 in tumor biopsies and cytological material of uterine cervical cancer.
Cancer letters - 25 Feb 2002
Manolaraki Maria M, Arvanitis Demetrios A, Sourvinos George, Sifakis Stavros, Koumantakis Eugenios, Spandidos Demetrios A
Abstract excerpt
Using polymerase chain reaction-based microsatellite analysis we examined 40 cases, tumor biopsies and cytological material, of early stage cervical cancer and 20 healthy donors. Loss of heterozygosity (LOH) was detected in 35 out of 40 cases (87.5%), located on 9pter-p13 (67.5%), 9q32-34 (17.5%), 13q12 (32.5%), 17p13 (0%) and 17q11-q22 (12.5%). Microsatellite instability (MIN) phenotype was found in three out of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
