Article
cis-acting elements in the U3 region of a simian immunodeficiency virus.
Journal of virology - 1 Jun 1990
Renjifo B, Speck N A, Winandy S, Hopkins N, Li Y
Abstract excerpt
A series of 5' deletions and a point mutation in the binding site for nuclear factor kappa B were introduced into the U3 region of a molecular clone of simian immunodeficiency virus from macaques (SIVmac142). The transcriptional activity of the mutated U3 regions was analyzed by transient chloram...
Topics
- Animals
- Base Sequence
- Cell Line
- Chloramphenicol O-Acetyltransferase
- Chromosome Deletion
- Cloning, Molecular
- Genes, Viral
- Humans
- Macaca
- Molecular Sequence Data
- Mutation
- Plasmids
- Promoter Regions, Genetic
- Regulatory Sequences, Nucleic Acid
- Repetitive Sequences, Nucleic Acid
- Simian Immunodeficiency Virus
- Transcriptional Activation