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Article

Activation of a cryptic splice donor in human immunodeficiency virus type-1.

Journal of biomedical science - 1 Jan 1999

Borg K T, Favaro J P, Arrigo S J, Schmidt M

Abstract excerpt

The human immunodeficiency virus type-1 regulatory protein Rev is absolutely required for the production of viral structural proteins. Splice sites have been seen to function as cis-acting repressor sequendes (CRS) and inhibit expression of the Rev-dependent RNAs. In order to analyze the role of...

Topics

Animals
Base Sequence
COS Cells
Cytoplasm
Gene Expression Regulation, Viral
Gene Products, gag
Gene Products, rev
HIV-1
Molecular Sequence Data
Mutation
RNA Splicing
RNA, Viral
Regulatory Sequences, Nucleic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Reverse Transcriptase Polymerase Chain Reaction

rev Gene Products, Human Immunodeficiency Virus

Source

Identifiers

PMID: 9933742
DOI: 10.1007/BF02256423

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9933742-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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