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Article

Activation of a cryptic splice donor in human immunodeficiency virus type-1.

Journal of biomedical science - 1 Jan 1999

Borg K T, Favaro J P, Arrigo S J, Schmidt M

Abstract excerpt

The human immunodeficiency virus type-1 regulatory protein Rev is absolutely required for the production of viral structural proteins. Splice sites have been seen to function as cis-acting repressor sequendes (CRS) and inhibit expression of the Rev-dependent RNAs. In order to analyze the role of a splice donor in Rev dependence, the wild-type 5' splice donor of HIV-1 was mutated in the context of other gag...

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Identifiers

PMID: 9933742
DOI: 10.1007/BF02256423

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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