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Article

A cis-Acting Element Downstream of the Mouse Mammary Tumor Virus Major Splice Donor Critical for RNA Elongation and Stability.

Journal of molecular biology - 19 Oct 2018

Akhlaq Shaima, Panicker Neena G, Philip Pretty S, Ali Lizna M, Dudley Jaquelin P, Rizvi Tahir A, Mustafa Farah

Abstract excerpt

BACKGROUND: The mouse mammary tumor virus (MMTV) encodes a functional signal peptide, a cleavage product of envelope and Rem proteins. Signal peptide interacts with a 3' cis-acting RNA element, the Rem-responsive element (RmRE), to facilitate expression of both unspliced genomic (gRNA) and spliced mRNAs. An additional RmRE has been proposed at the 5' end of the genome, facilitating nuclear export of the unspliced...

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Identifiers

PMID: 30179605
DOI: 10.1016/j.jmb.2018.08.025
PMCID: PMC6193448

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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