Article
The highly structured encapsidation signal of MuLV RNA is involved in the nuclear export of its unspliced RNA.
Journal of molecular biology - 16 Dec 2005
Smagulova Fatima, Maurel Stéphan, Morichaud Zakia, Devaux Christian, Mougel Marylène, Houzet Laurent
Abstract excerpt
The encapsidation signal (Psi) of retroviruses is located in the 5' UTR of the viral genomic unspliced transcript and is highly structured. In the Psi of murine leukaemia virus (MuLV), four stem-loops, called A, B, C and D, promote dimerization and encapsidation of the MuLV unspliced RNA into vir...
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