Article
Upstream and downstream cis-acting elements for cleavage at the L4 polyadenylation site of adenovirus-2.
Nucleic acids research - 25 Jan 1994
Sittler A, Gallinaro H, Jacob M
Abstract excerpt
A study of the cis-acting elements involved in the 3' end formation of the RNAs from the major late L4 family of adenovirus-2 was undertaken. Series of 5' or 3' end deletion mutants and mutants harboring either internal deletions or substitutions were prepared and assayed for in vitro cleavage. This first allowed the demonstration of a sequence, located at -6 to -29, relative to AAUAAA, whose deletion or...
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