Article
Multiple cis elements regulate an alternative splicing event at 4.1R pre-mRNA during erythroid differentiation.
Blood - 15 Dec 2001
Deguillien M, Huang S C, Morinière M, Dreumont N, Benz E J, Baklouti F
Abstract excerpt
The inclusion of exon 16 in the mature protein 4.1R messenger RNA (mRNA) is a critical event in red blood cell membrane biogenesis. It occurs during late erythroid development and results in inclusion of the 10-kd domain needed for stabilization of the spectrin/actin lattice. In this study, an experimental model was established in murine erythroleukemia cells that reproduces the endogenous exon 16 splicing...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
