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Article

Does simultaneous consideration of multiple regions improve disease gene localization?

Genetic epidemiology - 1 Jan 2001

Biernacka J, Lewinger J P, Chan V, Bull S B

Abstract excerpt

Improvement in localization of disease susceptibility genes by simultaneous consideration of multiple interacting loci was assessed using the Genetic Analysis Workshop 12 simulated data. Evidence of linkage at primary loci was used to weight families for analyses at secondary loci. To identify regions linked to disease susceptibility genes, parametric and allele-sharing genome scans were performed in the extended...

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PMID: 11793727
DOI: 10.1002/gepi.2001.21.s1.s504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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