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Article

Role of LncRNA H19/miR-93-5p/Orai1 axis in the regulation of human bronchial smooth muscle cell functions and airway remodeling in murine models of asthma

2021-07-13

Abstract excerpt

<title>Abstract</title> <p>Background Type 2 cytokine Interleukin (IL)-13 regulates airway remodeling in asthma by acting on store-operated Ca<sup>2+</sup> entry (SOCE) in airway smooth muscle cells. The underlying mechanisms of this regulating effect of IL-13 are not fully understood. Methods Bioinformatic analysis identified interactions of microRNA 93-5p with Orai1, the pore-forming molecule of SOCE, and lon...

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Literature Corpus work
e54ea3e0-4426-5025-98b8-ba80e29f76db
DOI
10.21203/rs.3.rs-681865/v1
Open publication

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Role of LncRNA H19/miR-93-5p/Orai1 axis in the regulation of human bronchial smooth muscle cell functions and airway remodeling in murine models of asthmaDOI 10.21203/rs.3.rs-681865/v1
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