Article
Interferon-gamma induces a cell surface phenotype switch on T84 intestinal epithelial cells.
The American journal of physiology - 1 Aug 1994
Colgan S P, Parkos C A, Matthews J B, D'Andrea L, Awtrey C S, Lichtman A H, Delp-Archer C, Madara J L
Abstract excerpt
Intestinal epithelia are in intimate contact with submucosal and intraepithelial lymphocytes. The concentration of intraepithelial lymphocytes increases during inflammatory processes, and, when stimulated, these cells generate cytokines such as interferon-gamma (IFN-gamma). In this study, we examined the effect of recombinant human IFN-gamma on ion transport events in T84 cells, a crypt epithelial cell line...
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