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Article

Epithelial barrier function properties of the 16HBE14o- human bronchial epithelial cell culture model

28 Sept 2020

Abstract excerpt

The human bronchial epithelial cell line, 16HBE14o- (16HBE), is widely used as a model for respiratory epithelial diseases and barrier function. During differentiation, transepithelial electrical resistance (TER) increased to approximately 800 Ohms × cm2, while 14C-d-mannitol flux rates (Jm) simultaneously decreased. Tight junctions (TJs) were shown by diffusion potential studies to be anion-selective with...

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PMID: 32985670
DOI: 10.1042/bsr20201532

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