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Article

FGF2 signaling is required for the development of neuronal circuits regulating blood pressure.

Circulation research - 11 Jan 2002

Dono Rosanna, Faulhaber Jörg, Galli Antonella, Zuniga Aimée, Volk Tilmann, Texido Gemma, Zeller Rolf, Ehmke Heimo

Abstract excerpt

Fibroblast growth factor 2 (FGF2) signaling is involved in angiogenesis, vascular contractility, and cardiac hypertrophy. Mice lacking a functional FGF2 gene (FGF2(-/-)) are hypotensive, but the primary physiological role of FGF2 in cardiovascular homeostasis remained unknown. Using a chicken FGF2 (cFGF2) transgene under control of the Wnt-1 promotor, we selectively re-expressed FGF2 in the developing nervous...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11786528

Genes

FGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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