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Article

Flow-dependent remodeling in the carotid artery of fibroblast growth factor-2 knockout mice.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 2002

Sullivan Chris J, Hoying James B

Abstract excerpt

OBJECTIVE: Fibroblast growth factor-2 (FGF2) has been implicated as a mediator in the structural remodeling of arteries. Chronic changes in blood flow are known to cause reorganization of the vessel wall, resulting in permanent changes in artery size (flow-dependent remodeling). Using FGF2 knockout (Fgf2(-/-)) mice, we tested the hypothesis that FGF2 is required during flow-dependent remodeling of the carotid...

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Source

Identifiers

PMID: 12117723
DOI: 10.1161/01.atv.0000023230.17493.e3

Genes

FGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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