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Article

Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage.

Nature - 1 Jan 2000

Ohta A, Sitkovsky M

Abstract excerpt

Inappropriate or prolonged inflammation is the main cause of many diseases; for this reason it is important to understand the physiological mechanisms that terminate inflammation in vivo. Agonists for several Gs-protein-coupled receptors, including cell-surface adenosine purinergic receptors, can increase levels of immunosuppressive cyclic AMP in immune cells; however, it was unknown whether any of these...

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PMID: 11780065
DOI: 10.1038/414916a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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