New insights into the regulation of inflammation by adenosine.

Abstract excerpt

Adenosine, long known as a regulator of cardiovascular function, has recently been identified as a significant paracrine inhibitor of inflammation that acts primarily by activation of A2A adenosine receptors (A2AARs) on lymphoid or myeloid cells. In this issue of the JCI, Yang et al. describe a proinflammatory phenotype resulting from deletion of the gene encoding the A2B adenosine receptor (A2BAR) in the mouse,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Adenosine
• Share to Inflammation
• Share to Mice