Article
Alveolar Epithelial A2B Adenosine Receptors in Pulmonary Protection during Acute Lung Injury.
Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 2015
Hoegl Sandra, Brodsky Kelley S, Blackburn Michael R, Karmouty-Quintana Harry, Zwissler Bernhard, Eltzschig Holger K
Abstract excerpt
Acute lung injury (ALI) is an acute inflammatory lung disease that causes morbidity and mortality in critically ill patients. However, there are many instances where ALI resolves spontaneously through endogenous pathways that help to control excessive lung inflammation. Previous studies have implicated the extracellular signaling molecule adenosine and signaling events through the A2B adenosine receptor in lung...
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